I-Horus Inc.

Fat Cell
Fat Cell

Regenerative Medicine is a paradigm shifting technology that will revolutionize global healthcare by curing or effectively treating the -patients- devastating acute and chronic diseases and conditions instead of the conventional medical options of treating the symptoms.


Regenerative medicine is a multidisciplinary field that combines the specialization of cellular, stem cell and developmental biology, tissue engineering, biochemistry, immunology, and other related disciplines that integrate to regeneratdamaged tissues and organs through various delivery, communication and signalling mechanisms that repair previously irreparable tissue and organs into healing and the restoring lost function and health.


Chronic diseases - such as heart    disease, cancer, and diabetes - are the leading causes of death and disability in the United States. These diseases account for 7 of    every 10 deaths and affect the quality of life of 133 million Americans – almost 1 out of every 2 adults – had at least one chronic illness. CDC Center for Disease Control and Prevention


Healthcare expenditures have grown more than twice the pace of the national gross domestic product (GDP), with nearly 75 cents of every healthcare dollar is (75%) spent on treatment of chronic diseases. Chronic diseases are No. 1 cause of death, illness, hospitalization, health care costs and long-term disability. Chronic disease affects every nation’s businesses and economy, reducing productivity    and placing an unsustainable burden on all sectors of society.


Can we reverse this devastating and unsustainable trend?  Yes we will.


Time is fast running out when we combine the increasing demographic tsunami of a rapidly aging population in industrialized countries with the costs of healthcare-for chronic diseases alone-that have grown to unprecedented levels. a fact emerges that is so evident that it cannot be debated or refuted is that maintaining the current healthcare system could well bankrupt the largest economies in the world.


It is this critical certainty of the healthcare dilemma for all people of the world; Regenerative Medicines potential to transform healthcare for all humanity should make it a priority at all healthcare levels; its relevance must be prioritized in the best interests of the economy, and contemporary society of every country.


iHorus/AppliCell members and our partners are impelled by these challenges to stand togetherto revolutionize healthcare through regenerative    medicine . 


What is the potential of tissue engineering regenerative medicine ? 

Dr. Alan Russell the chairman of our scientific board speaks at the TED Talks conference on the potential of regenerative medicine.

About OrCel®

Product Description
OrCel® is a bilayered cellular matrix in which normal human allogeneic skin cells (epidermal keratinocytes and dermal fibroblasts) are cultured in two separate layers into a Type I bovine collagen sponge. Donor dermal fibroblasts are cultured on and within the porous sponge side of the collagen matrix while keratinocytes, from the same donor, are cultured on the coated, non-porous side of the collagen matrix.

OrCel® serves as an absorbable biocompatible matrix that provides a favorable environment for host cell migration and has been shown to contain the following cell-expressed cytokines and growth factors: FGF-1 (bFGF), NGF, GM-CSF, IL-1a, IL-1b, IL-6, HGF, KGF-1 (FGF-7), M-CSF, PDGF-AB, TGF-a, TGF-b1, TGF-b2, and VEGF. OrCel® is not intended to be a human skin replacement and does not contain Langerhans cells, melanocytes, macrophages, lymphocytes, blood vessels or hair follicles. DNA analysis performed on two OrCel® -treated donor site patient tissue samples showed no trace of allogeneic cell DNA after two or three weeks respectively.





現在、アメリカ国内では、表皮水疱症 (Epidermolysis bullosa, EB)と火傷でFDAから製造販売承認を受けております。










表皮水疱症 Epidermolysis bullosa, EB


OrCel®は、アメリカのFDA(食品医薬品局)より表皮水疱症 Epidermolysis bullosa, EBの治療剤として認可されております。


当社の子会社であるApplicell KK.の治療技術である、3T3ライン(マウス由来細胞)を使用しないヒト細胞由来シートを使用した治療のご紹介です。






糖尿病壊疽 diabetic gangrene






Tailor-made Cosmetics  AppliCell 






i-Horus Inc.は、世界で始めて患者自身の幹細胞を使用した Tailor-made Cosmetics  AppliCell 製品の製造開発に成功し、世界のVIPのお客様に愛されてきました